生化学Ⅱ/分子生物学/細胞生物学/薬学基礎実習/生物系実習Ⅰ,Ⅱ/特別実習

主な研究テーマ

1. 神経回路形成に関わるダブルコルチン様キナーゼの分子メカニズムの解明
2. 発達障害モデルマウスを用いた衝動性の神経基盤の解明

研究論文

1. Maejima I, Hara T, Tsukamoto S, Koizumi H, Kawauchi T, Akuzawa T, Hirai R, Kobayashi H, Isobe I, Emoto K, Kosako H, Sato K: RAB35 is required for murine hippocampal development and functions by regulating neuronal cell distribution. Communications Biology 6(1):440 (2023)
2. Bargoglio E, Suzuki IK^*, Togashi K, Tsuji M, Takeuchi S, Koizumi H^*, Emoto K^*: Spatial and temporal diversity of DCLK1 isoforms in developing mouse brain.  Neuroscience Research 170:154-165 (2021)
3. Togashi K, Tsuji M, Takeuchi S, Nakahama R, Koizumi H, Emoto K^*: Adeno-Associated Virus-Mediated Single-Cell Labeling of Mitral Cells in the Mouse Olfactory Bulb: Insights into the Developmental Dynamics of Dendrite Remodeling. Front Cell Neurosci. 14:572256 (2020) 
4. Koizumi H^*, Fujioka H, Togashi K, Thompson J, Yates JR, 3rd, Gleeson JG, Emoto K^*: DCLK1 phosphorylates the microtubule-associated protein MAP7D1 to promote axon elongation in cortical neurons. Dev Neurobiol 77:493-510 (2017)
5. Yasunaga K, Tezuka A, Ishikawa N, Dairyo Y, Togashi K, Koizumi H, Emoto K^*: Adult Drosophila sensory neurons specify dendritic territories independently of dendritic contacts through the Wnt5-Drl signaling pathway. Genes Dev. 29(16):1763-1775. (2015)
6. Kanamori T, Togashi K, Koizumi H, Emoto K^*: Dendritic Remodeling: Lessons from Invertebrate Model Systems. Int Rev Cell Mol Biol. 318:1-25. (2015)
7. Shin E, Kashiwagi Y, Kuriu T, Iwasaki H, Tanaka T, Koizumi H, Gleeson JG, Okabe S^*: Doublecortin-like kinase enhances dendritic remodeling and negatively regulates synapse maturation. Nature Commun 4:1440 (2013)

 

 

 

https://www.researchgate.net/profile/Hiroyuki_Koizumi3/research

https://researchmap.jp/hkoizumi/published_papers

• 北米神経科学会
• 日本薬学会
• 日本神経科学学会