物理薬剤学/製剤学/物理系実習/薬剤学実習/基礎薬学計算/基礎薬学実習(物理)

主な研究テーマ

1. 電気刺激応答型薬物放出システムの開発
2. 交互累積膜法を用いた薬物送達システムの開発

研究論文

1. Highly sensitive glucose electrochemical sensor using sugar‐lectin interactions. Kyoko Sugiyama, Fumiya Sato, Sachiko Komatsu, Toshio Kamijo, Kentaro Yoshida, Yusuke Kawabe, Hiromi Nishikawa, Tsutomu Fujimura, Yasufumi Takahashi, Katsuhiko Sato, Electrochemical Science Advances 2023, https://doi.org/10.1002/elsa.202300015

2. Determination of antibiotics by amperometry using nortropine N-oxyl, a highly active nitroxyl radical. Tetsuya Ono, Fumiya Sato, Masayuki Kumano, Sachiko Komatsu, Kyoko Sugiyama, Kazuhiro Watanabe, Kentaro Yoshida, Yusuke Sasano, Tsutomu Fujimura, Yoshiharu Iwabuchi, Yoshitomo Kashiwagi, Katsuhiko Sato, Analytical Sciences 2023, https://doi.org/10.1007/s44211-023-00388-4

3. Electrochemical Reactions of Highly Active Nitroxyl Radicals with Thiol Compounds. Masayuki Kumano; Kyoko Sugiyama; Fumiya Sato; Sachiko Komatsu; Kazuhiro Watanabe; Tetsuya Ono; Kentaro Yoshida; Yusuke Sasano; Yoshiharu Iwabuchi; Tsutomu Fujimura; Yoshitomo Kashiwagi; Katsuhiko Sato, Analytical Sciences, 2022, https://doi.org/10.1007/s44211-022-00246-9
4. Electrical Stimuli-Responsive Decomposition of Layer-by-Layer Films Composed of Polycations and TEMPO-Modified Poly(acrylic acid) Kentaro Yoshida, Toshio Kamijo, Tetsuya Ono, Takenori Dairak, Shigehiro Takahashi, Yoshitomo Kashiwagi, Katsuhiko Sato, Polymers 2022, 14(24), 5349; https://doi.org/10.3390/polym14245349
5. Electrochemical Polymerization of Nitroxyl Radical Precursor Containing Phenol Side Chain in Aqueous Solution and Its Application to Electrochemical Analysis of Glucose Katsuhiko SATO, Masayuki KUMANO, Kyoko SUGIYAMA, Sachiko KOMATSU, Kazuhiro WATANABE, Ryota IMAHASHI, Tetsuya ONO, Kentaro YOSHIDA, Takenori DAIRAKU, Tsutomu FUJIMURA, Yoshitomo KASHIWAGI, BUNSEKI KAGAKU 2022, 71, 191-196
6. Nitroxyl Radical/Copper-Catalyzed Electrooxidation of Alcohols and Amines at Low Potentials Kyoko Sugiyama, Yusuke Sasano, Sachiko Komatsu, Kentaro Yoshida, Tetsuya Ono, Tsutomu Fujimura, Yoshiharu Iwabuchi, Yoshitomo Kashiwagi, Katsuhiko Sato Chemical and Pharmaceutical Bulletin 69(10) 1005-1009 2021
7. Chemical reduction of Ag+ to Ag employing organic electron donors: evaluation of the effect of Ag+-mediated cytosine–cytosine base pairing on the aggregation of Ag nanoparticles. Takenori Dairaku, Rika Kawai, Kanako Nozawa-Kumada, Kentaro Yoshida, Tetsuya Ono, Yoshinori Kondo, Jiro Kondo, Akira Ono, Yoshiyuki Tanaka, Yoshitomo Kashiwagi, Dalton Transactions 2021, 50, 12208-12214
8. Catalysis of electro-oxidation of antibiotics by nitroxyl radicals and the electrochemical sensing of vancomycin. Tetsuya Ono, Kyoko Sugiyama, Sachiko Komatsu, Masayuki Kumano, Kentaro Yoshida, Takenori Dairaku, Tsutomu Fujimura, Yusuke Sasano, Yoshiharu Iwabuchi, Yoshitomo Kashiwagi, Katsuhiko Sato, RSC Advances 2021, 11,21622-21628
9. Effect of cytosine–Ag+–cytosine base pairing on the redox potential of the Ag+/Ag couple and the chemical reduction of Ag+ to Ag by tetrathiafulvalene. Takenori Dairaku, Rika Kawai, Teppei Kanaba, Tetsuya Ono, Kentaro Yoshida, Hajime Sato, Kanako Nozawa-Kumada, Yoshinori Kondo, Jiro Kondo, Akira Ono, Yoshiyuki Tanaka, Yoshitomo Kashiwagi, Kashiwagi, Dalton Transactions 2021, 50,7633-7639
10. Electrochemical Evaluation of Nitroxyl Radical Catalysts and Electrochemical Detection of Cyclosporin A. Sachiko Komatsu , Yusuke Sasano , Kyoko Sugiyama , Kazuhiro Watanabe , Masayuki Kumano , Kentaro Yoshida , Tetsuya Ono , Yoshiharu Iwabuchi , Tsutomu Fujimura , Katsuhiko Sato , Yoshitomo Kashiwagi, Int. J. Electrochem. Sci. 2021, 16 Article ID: 21027, doi: 10.20964/2021.02.30 
11. Electropolymerization of Azure A and pH sensing using poly(Azure A)-modified electrodes. Kyoko SUGIYAMA, Kazuhiro WATANABE, Sachiko KOMATSU, Kentaro YOSHIDA, Tetsuya ONO, Tsutomu FUJIMURA, Yoshitomo KASHIWAGI, Katsuhiko SATO, Analytical Sciences 2020, DOI: 10.2116/analsci.20P341
12. Voltammetric pH Measurements Using Azure A-Containing Layer-by-Layer Film Immobilized Electrodes. Kazuhiro Watanabe, Kyoko Sugiyama, Sachiko Komatsu, Kentaro Yoshida, Tetsuya Ono, Tsutomu Fujimura, Yoshitomo Kashiwagi, Katsuhiko Sato, Polymers 2020, 12, 2328 - 2328
13. Adsorption and Release of Rose Bengal on Layer-by-Layer Films of Poly(Vinyl Alcohol) and Poly(Amidoamine) Dendrimers Bearing 4-Carboxyphenylboronic Acid. Kentaro Yoshida , Akane Yamaguchi , Hiroki Midorikawa , Toshio Kamijo , Tetsuya Ono , Takenori Dairaku , Takaya Sato , Tsutomu Fujimura , Yoshitomo Kashiwagi and Katsuhiko Sato, polymers 2020, 12, 1854
14.  Decomposition of Glucose-Sensitive Layer-by-Layer Films Using Hemin, DNA, and Glucose Oxidase. Kentaro Yoshida, Yu Kashimura, Toshio Kamijo, Tetsuya Ono, Takenori Dairaku, Takaya Sato, Yoshitomo Kashiwagi, Katsuhiko Sato, polymers  2020, 12, 319
15. Electrochemical determination of choline using nortropine-N-oxyl for a non-enzymatic system. Yoshitomo Kashiwagi, Tetsuya Ono, Fumiya Sato, Masayuki Kumano, Kentaro Yoshida, Takenori Dairakua, Yusuke Sasano, Yoshiharu Iwabuchi, Katsuhiko Sato, Sensing and Bio-Sensing Research 2020, 27, 100302
16. Electrochemical detection of triglycerides based on an enzymatic reaction and electrocatalytic oxidation with nortropine‐N‐oxyl. Tetsuya Ono, Katsuhiko Sato, Yusuke Sasano, Kentaro Yoshida, Takenori Dairaku, Yoshiharu Iwabuchi,Yoshitomo Kashiwagi, Electroanalysis 2019, 31, 603-606
17.  Preparation of hydrogen peroxide sensitive nanofilms by layer-by-layer technique. Kentaro Yoshida, Tetsuya Ono, Takenori Dairaku, Yoshitomo Kashiwagi, Katsuhiko Sato, nanomaterials 2018, 8, 941
18.  Electrochemical oxidation of amines using a nitroxyl radical catalyst and the electroanalysis of lidocaine. Katsuhiko Sato, Tetsuya Ono, Yusuke Sasano, Fumiya Sato, Masayuki Kumano, Kentaro Yoshida, Takenori Dairaku, Yoshiharu Iwabuchi, Yoshitomo Kashiwagi, Catalysts 2018, 8, 649
19. Preparation of microparticles capable of glucose-induced insulin release under physiological conditions. Kentaro Yoshida, Kazuma Awaji, Seira Shimizu, Miku Iwasaki, Yuki Oide, Megumi Ito, Takenori Dairaku, Tetsuya Ono, Yoshitomo Kashiwagi, Katsuhiko Sato, polymers 2018, 10, 1164
20. Preparation of nafion/polycation layer-by-layer films for adsorption and release of insulin. Kentaro Yoshida, Katsuhiko Sato, Tetsuya Ono, Takenori Dairaku, Yoshitomo Kashiwagi, polymers 2018, 10, 812
21. Preparation of multilayer films using the negative charge of phenylboronic acid and its response to pH change, fructose, and hydrogen peroxide. Yuki Oide, Miku Iwasaki, Kentaro Yoshida, Katsuhiko Sato, Colloid and Polymer Science 2018, 296, 1573-1580
22. Construction of PQQ-enzyme multi-immobilized electrodes for electrocatalytic reduction of formate. Yoshitomo Kashiwagi, Tetsuya Ono, Kentaro Yoshida, Toshinori Ito, Nobuki Sakurai, Heterocycles 2018, 96, 1216-1225
23. Electrocatalytic oxidation of carbohydrates mediates by nitroxyl radical-modified electrodes inaqueous solution. Yoshitomo Kashiwagi, Yumiko Takamori, Kentaro Yoshida, Tetsuya Ono, Electroanalysis 2018, 30, 24-26
24.  交互累積膜法による高機能性高分子ナノ薄膜の開発. 吉田健太郎, YAKUGAKU ZASSHI 2017, 137, 1215-1221
25. Phenylboronic acid-functionalized layer-by-layer assemblies for biomedical applications. Baozhen Wang, Kentaro Yoshida, Katsuhiko Sato, Jun-ichi Anzai, polymers 2017, 9, 202
26. Preparation of layer-by-layer films composed of polysaccharides and poly(amidoamine) dendrimer bearing phenylboronic acid and their pH- and sugar-dependent stability. Kentaro Yoshida, Keisuke Suwa, Jun-ichi Anzai, Materials 2016, 9, 425
27.  pH- and sugar-sensitive multilayer films composed of phenylboronic acid (PBA)-modified poly(allyamine hydrochloride) (PBA-PAH) and poly (vinyl alcohol) (PVA): A significant effect of PBA content on the film stability. Masaru Seno, Kentaro Yoshida, Katsuhiko Sato, Jun-ichi Anzai, Materials Science and Engineering C 2016, 62, 474-479
28. Electrochemical determination of D-glucose using nortropine N-oxyl under physiological conditions. Katsuhiko Sato, Tetsuya Ono, Kentaro Yoshida, Toshinori Ito, Yoshitomo Kashiwagi, Electoroanalysis 2015, 10, 2272-2274
29. pH-dependent release of insulin from layer-by-layer-deposited polyelectrolyte microcapsules. Kentaro Yoshida, Tetsuya Ono, Yoshitomo Kashiwagi, Shigehiro Takahashi, Katsuhiko Sato, Jun-ichi Anzai, Polymers 2015, 7, 1269-1278
30. Poly(lactic acid) Microparticles Coated with Insulin-Containing Layer-by-Layer Films and Their pH-Dependent Insulin Release Ryosuke Hashide, Kentaro Yoshida, Yasushi Hasebe, Masaru Seno, Shigehiro Takahashi, Katsuhiko Sato, Jun-Ichi AnzaiJOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 14(4) 3100-3105 2014
31.  Layer-by-layer deposited nano- and micro-assemblies for insulin delivery: A review. Kentaro Yoshida, Yasushi Hasebe , Shigehiro Takahashi , Katsuhiko Sato , Jun-ichi Anzai, Materials Science and Engineering: C 2014, 34, 384-392
32.  Electrocatalytic oxidation of amines on a mediator-modified electrode by electrochemical copolymerization of nitroxyl radical precursor. Yoshitomo Kashiwagi, Yumiko Takamori, Kentaro Yoshida, Tetsuya Ono, Electoroanalysis 2013, 25, 2575-2577
33.  Use of anionic polysaccharides for the preparation of insulin-containing layer-by-layer films and their pH stability. Ryosuke Hashide, Kentaro Yoshida, Kenta Kotaki, Takumi Watanabe, Ryota Watahiki, Shigehiro Takahashi, Katsuhiko Sato, Jun-ichi Anzai, Polymer Bulletin 2012, 69, 229?239
34. Layer-by-layer films composed of poly(allyamine) and insulin for pH-triggerd release of insulin.　 Kentaro Yoshida, Ryosuke Hashide, Tsuyoshi Ishii, Shigehiro Takahashi, Katsuhiko Sato, Jun-ichi Anzai, Colloids and surfaces B: Biointerfaces 2012, 91, 274-279
35. Insulin-containing layer-by-layer films deposited on poly(lactic acid) microbeads for pH-controlled release of insulin. Ryosuke Hashide, Kentaro Yoshida, Yasushi Hasebec, Shigehiro Takahashi, Katsuhiko Sato, Jun-ichi Anzai, Colloids and surfaces B: Biointerfaces 2012, 89, 242-247 
36. Voltammetric determination of salicylic acid and derivatives based on ferroceneboronic acid. Shigehiro Takahashi, Nobuhiro Haraguchi, Naoyuki Abiko, Tetsuya Ono, Kentaro Yoshida, Jun-ichi Anzai, Sensor Letters 2011, 9, 1845-1848
37. pH- and sugar-sensitive layer-by-layer films and microcapsules for drug delivery. Katsuhiko Sato, Kentaro Yoshida, Shgehiro Takahashi, Jun-ichi Anzai, Advanced Drug Delivery Reviews 2011, 63, 809-821
38. Voltammetric response of ferroceneboronic acid to diol and phenolic compounds as possible pollutants. Shigehiro Takahashi, Naoyuki Abiko, Nobuhiro Haraguchi, Hiroyuki Fujita, Eriko Seki, Tetsuya Ono, Kentaro Yoshida, Jun-ichi Anzai, Journal of environmental Sciences 2011, 23, 1027-1032
39. Colorimetric response of fluorescein-modified multilayer thin films induced by electrolysis of water. Munenari Nagasaka, Kentaro Yoshida, Shigehiro Takahashi, Katsuhiko Sato, Jun-ichi Anzai, Materials Science and Engineering C 2011, 31, 258-261

  全44報 査読有　https://researchmap.jp/ky1983/published_papers

• 日本薬学会
• 化学センサ研究会