馬場　優 教授 博士(医学)

総合臨床医学講座は、3つの医科系分野、すなわち内科学分野、外科学分野、耳鼻咽喉科学分野からなる。歯学部学生の教育においては、歯科医師や歯科医学研究者に必要な臨床医学の知識や、健康な生活を送るための基本的な考え方を講義している。また、特に、近年増加している医科系の疾患をもった有病者に対する歯科診療のあり方を理解させている。

研究活動では、口腔生化学教室と共同研究を行っており、“奥羽大学から世界に情報を発信”を合言葉に、歯学部における医科系講座の特色を生かした研究活動を積極的に進めている。

奥羽大学病院における診療活動は、外来患者の診察、検査、治療を行っている。歯科系の診察科から医科系の疾患をもった有病者の紹介が増加し、安全な歯科医療の推進のために貢献できるよう努力している。

1. 頭頸部扁平上皮癌におけるmolecular biology
2. アレルギー性鼻炎
3. インプラント治療における医科歯科連携
4. 医療安全
5. 院内感染対策

馬場　優

ババ　ユウ

教授

 

• 日本耳鼻咽喉科学会
• 日本頭頸部癌学会
• 日本頭頸部外科学会
• 日本気管食道科学会
• 日本口腔咽頭科学会
• 耳鼻咽喉科臨床学会
• 日本臨床腫瘍学会
• 日本アレルギー学会
• 日本甲状腺外科学会
• 奥羽大学歯学会
• 日本口腔科学会
• 日本耳鼻咽喉科感染症・エアロゾル学会
• 日本環境感染学会
• 日本産業衛生学会

論文(2010年以降)

英文

1.  Yuh Baba, Yasumasa Kato, and Keiso Takahashi. Proposal for a paradigm shift in personalized medicine for patients with a maxillary edentulous jaw by ENT specialist and dentist cooperation. J Pers Med, 12: 1289, 2022. 

2. Yuh Baba, Keiso Takahashi, and Yasumasa Kato. The management of periodontitis patients should not be postponed during the COVID-19 Era. On J Dent and Oral health, 5: 3, 2022.

3.Yuh Baba, Satoshi Takada, and Yasumasa Kato. In Reference to risk perception of septic shock with multiple organ failure due to acute exacerbation of an infectious dental disease. Ther Clin Risk Manag, 17: 1163-1164, 2021 

4. Keiso Takahashi, Kosaku Yamazaki, Mikiko Suzuki-Yamazaki, Hiroshi Ito, and Yuh Baba. Different management for patients with two types of chronic rhinosinusitis for their oral implant therapy. Adv Dent and Oral Health, 14: 555894, 2021.

5. Tatsuo Funakawa, Hitoshi Kawanabe, Akinobu Usami, Keiso Takahashi, Yasumasa Kato, Yuh Baba. The importance of early detection for postoperative maxillary cyst before dental implantation: A case report. Int. J. Surg. Case. Rep, 86: 106370, 2021. 

6.Yuh Baba, Satoshi Takada, Yasumasa Kato. In Reference to COVID-19 and the Otolaryngologist: Preliminary Evidence-based Review. Laryngoscope. 2021 Jan 31. doi: 10.1002/lary.29412.

7. Shiori Oka, Hitoshi Kawanabe, Shinya Yamanobe, Kazunori Fukui, Yuh Baba, Toru Deguchi. Relationship between olfaction and maxillofacial morphology in children with malocclusion. Clinical and experimental dental research, 2021 Feb;7(1):33-39. doi: 10.1002/cre2.329.

8. Mikiko Suzuki-Yamazaki, Keiso Takahashi, Satoshi Takada, Yasumasa Kato, and Yuh Baba. A successful treatment regimen for the prevention of sinusitis after maxillary sinus floor elevation surgery in a high-risk case. Case Reports in Otolaryngology, vol. 2020, Article ID6869805, 3 pages, 2020.

9. Yuh Baba, Satoshi Takada, Hiroshi Segawa, and Yasumasa Kato. Different management between emergent infectious diseases and emergent non-infectious diseases during COVID-19 pandemic in a head and neck unit. Brazilian Journal of infectious diseases 2020.

10. Yuh Baba and Yasumasa Kato. Confusion of EpiPen trainer with EpiPen caused by a pharmacist. Journal of paediatrics and child health 2020, 56, 826-7.

11. Yuh Baba and Yasumasa Kato. Neutrophil to lymphocyte ratio as biomarkers in head and neck squamous cell carcinoma. Biomarkers Journal2018, 4 (2), 12

12. Yuh Baba and Yasumasa Kato. An unexpected accidental ingestion of dental crown with loop: a clinical image. Journal of Case Reports and Medical Images. 2018; 1: 1004.

13. Mikiko Suzuki, Keiso Takahashi, Yasumasa Kato and Yuh Baba. A maxillary sinusitis after sinus lift surgery. Journal of Dentistry and oral disorders,4, 4, 1100, 2018.

14. Toshie Watanabe, Yasumasa Kato and Yuh Baba. An unexpected accidental needle-stick injury. Journal of Dentistry and oral disorders, 4, 3, 1094, 2018.

15.Yuh Baba and Yasumasa Kato. Deguelin, a novel anti-tumorigenic agent in human esophageal squamous cell carcinoma. Journal of the EBioMedicine, 26, 10, 2017 IF6.183

16.Yasumasa Kato, Yuh Baba, et al. Cancer metabolism: new insights into classic characteristics. Japanese Dental Science Review 2018, 54, 8-21.

17.Yuh Baba, Yasumasa Kato. Promising biomarkers to predict the efficacy of inhibitors of the epidermal growth factor receptor tyrosine kinase in head and neck squamous cell carcinoma. Biomarkers Journal 2017, 3, 1-3

18.Yuh Baba, Toyonobu Maeda, Atsuko Maeda, Satoshi Takada, Masato Fujii, and Yasumasa Kato. Deguelin potentiates apoptotic activity of an EGFR tyrosine kinase inhibitor (AG1478) in PIK3CA-mutated head and neck squamous cell carcinoma. Int. J. Mol. Sci. 2017, 18, 262, IF3.687 

19. Yuh Baba, Yasumasa Kato. Concomitant Crown and Piece of Tray Ingestion: A Case Report. J Med Cases 2016. 7(11)478-479.

20. Maeda T, Yuzawa S, Suzuki A, Baba Y, Nishimura Y, Kato Y. RhoA mediates the expression of acidic extracellular pH-induced matrix metalloproteinase-9 mRNA through phospholipase D1 in mouse metastatic B16-BL6 melanoma cells. Int J Oncol. 2016 Mar; 48(3):1251-1257.IF3.333  

21. Yuh Baba, Yasumasa Kato. The role of bavacizumab in the management of Head and Neck Squamous Cell Carcinoma Patients, Chemo Open Access 4:163. doi:10.4172/2167-7700.1000163 , 2015.

22. Toyonobu Maeda, Atsuko Suzuki, Satoshi Yuzawa, Yuh Baba, Yuichi Kimura, and Yasumasa Kato. Mineral trioxide aggregate induces osteoblastogenesis via Atf6, Bone Reports, 2, (2015), 36-43.

23. Yuh Baba, Masato Fujii, Toyonobu Maeda, Atsuko Suzuki, Satoshi Yuzawa, and Yasumasa Kato Deguelin Induces Apoptosis by Targeting Both EGFR-Akt and IGF1R-Akt Pathways in Head and Neck Squamous Cell Cancer Cell Lines BioMed Research International, vol. 2015, Article ID 657179, 9 pages, 2015, IF2.583

24. Suzuki A, Maeda T, Baba Y, Shimamura K, Kato Y. Acidic extracellular pH promotes epithelial mesenchymal transition in Lewis lung carcinoma model. Cancer Cell Int. 2014 Nov 30;14(1):129.IF3.960

25. Nishiyama T, Kato Y, Baba Y. Nasopharyngeal leiomyomatous hamartoma: case report. BMC Ear Nose and Throat Disorders, 14:5, 2014

26. Baba Y, Nishiyama T, Kato Y. Diagnosis and treatment of accessory parotid gland tumors. International Manual of Oncology Practice, 2014

27. Kato, Y, Ozawa S, Miyamoto C, Maehata Y, Suzuki A, Maeda T, Baba Y. Acidic etracellular microenvironmental and cancer. Cancer Cell International, 13: 89, 2013. (3.960)

28. Baba Y, Yoshihama K, Nishiyama T, and Kato Y. Levocetirizine hydrochloride tablet improves the nasal conditions of patients with cedar pollen allergy and maintains their QOL. Clinical and Experimental Medical Sciences, 2013, 1;7:329-341.                                                         

29. Yoshihama K, Kato Y, and Baba Y. Vocal cord actinomycosis mimicking a laryngeal tumor. Case Reports in Otolaryngology, vol. 2013, Article ID361986, 2 pages, 2013.

30. Baba Y, Fujii M, Tokumaru Y, Kato Y. Overcoming Resistance to EGFR inhibitor in HNSCC. The Research and Biology of Cancer II, chapter24, 2013.

31. Baba Y, Fujii M, Tokumaru Y, Kato Y. Cetuximab for Head and Neck Cancer from bench to clinic. Journal of Solid Tumors, 2012, Vol.2, No.6, 16-22.

32. Yoshihama K, Kato Y, and Baba Y. Xanthogranuloma of the external auditory canal mimicking a benign tumor: A Case Report. Case Reports in Otolaryngology, vol, 2012, 2012.

33. Baba Y, Fujii M, Tokumaru Y, Kato Y. Present and Future of EGFR inhibitors for Head and Neck Squamous Cell Cancer. Journal of Oncology, vol. 2012, 9pages, 2012. IF4.528

34. Baba Y, Fujii M, Tokumaru Y, Kato Y. Cell Signalings and the Communications in Head and Neck Cancer. Head and Neck Cancer, 2012, 123-140.

35. Baba Y, Kato Y. Hemangioma with phleboliths in the floor of the mouth presenting as a submental swelling: a case report. Journal of Medical Cases, 2011; 2; 1: 28-30.

36. Baba Y, Kato Y, Ogawa K. Unusual computed tomography findings of radionecrosis after chemoradiation of stage IV hypopharyngeal cancer: a case report. Journal of Medical Case Reports, 2011; 5; 1: 25.

37. Baba Y, Kato Y, Ogawa K. Hyperplasia of lymphoid structures in the hypopharynx: a case report. Journal of Medical Case Reports, 2010; 4(1): 388

38. Baba Y, Fujii M, Tokumaru Y, Kato Y. New strategy in Head and Neck Cancer: combination therapy targeting the PI3Kinase/Akt and EGFR signaling pathways. Hypotheses in Clinical Medicine,Chapter12, 2012.

39. Baba Y, Kato Y, Ogawa K. Inostamycin prevents malignant phenotype of cancer: inhibition of phosphatidylinositol synthesis provides a therapeutic advantage for head and neck squamous cell carcinoma. Cell Biol.Int, 2010; 14; 34; 2: 171-175. IF1.936

 

和文

1. 千葉俊美、山田浩之、馬場優、高田訓他、歯科医師のための内科学、医歯薬出版、2021
2. 馬場優、渡部敏恵、瀬川洋、奥羽大学病院内に集団発生した夏期インフルエンザへの早期対応、みちのく歯科学会誌、50(1-2), 71-73, 2019
3. 馬場優、瀬川洋、歯科治療中に発生した気道・消化管異物症例の検討、みちのく歯科学会誌、49(1-2), 77-79, 2018
4. 渡部敏恵、衛藤雅昭、小池勇一、佐藤研、加藤靖正、馬場優、4種ウイルス感染症における抗体陽性率および感受性率の年次推移について―麻疹・風疹・ムンプス・水痘の血清抗体価解析―, Campus Health 56(2), 104-110, 2019
5. 馬場優、高田訓、加藤靖正、口腔癌におけるEGFR阻害剤の効果予測因子、BIO Clinica 34(9), 921-923, 2019
6. 馬場優、瀬川洋、佐藤穏子、高橋昌宏、川原一郎、長谷川淳子、渡部敏恵、小嶋忠之、杉田俊博、奥羽大学歯学部附属病院における医療従事者のインフルエンザワクチン接種の現状と課題、奥羽大学歯学誌44巻3-4, 71-75, 2017
7. 前田豊信、鈴木厚子、湯澤仁、馬場優、加藤靖正　CRISPR/Cas9 を用いたMC3T3-E1 細胞におけるGpr81遺伝子のノックアウト、奥羽大学歯学誌41巻3-4, 123-128, 2014
8. 馬場優、西山 崇経、吉浜 圭祐　上頸部神経鞘腫手術におけるNerve Integrity Monitoring(NIM)の有用性、耳鼻咽喉科臨床, 107: 153-158, 2014
9. 吉浜圭祐_、川井俊郎、小川郁_、馬場優、鼻腔腺様嚢胞癌の1例、耳鼻咽喉科・頭頸部外科,85: 711-714, 2013
10. 馬場優、頭頸部癌に対する分子標的薬治療、耳鼻咽喉科臨床、106(1):89-93, 2013
11. 吉浜圭祐、小川裕介_、小川郁_、馬場優、診断に苦慮した大耳介神経断端神経腫の1例、耳鼻咽喉科・頭頸部外科,84(11):784-786, 2012
12. 小川裕介、小川郁、田代昌継、馬場優、口腔底脂肪種の1例、耳鼻咽喉科・頭頸部外科、83(9):685-687, 2011
13. 馬場優、小川裕介、小川郁　側頸部に発生した石灰化上皮腫の1例、耳鼻咽喉科・頭頸部外科、83(7):503-505, 2011
14. 馬場優、田代昌継、行木英生、小川郁、慢性副鼻腔炎を伴った篩骨洞骨腫の1例, 耳鼻咽喉科・頭頸部外科, 83(2): 155-157, 2011
15. 馬場優、小川郁、小児頸部キャッスルマン病の1例、耳鼻咽喉科・頭頸部外科, 82(4): 309-311, 2010