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教員紹介

山岸 丈洋 教授 [Takehiro Yamagishi]

担当授業科目
  • 化学I
  • 有機化学I
  • 有機化学II
  • 有機化学実演
  • 化学系実習
  • 特別実習

主な研究
主な研究テーマ

  1. リン原子の特性を利用したホスフィン酸誘導体の合成研究
  2. 連続反応を基盤とするフェノール誘導体の新合成法の開発


研究論文
  1. Nickel-catalyzed C-P Cross-coupling Reactions of Aryl Iodides with H-phosphinates. Kinbaram,A.; Ito,M; abe,T.Yamagishi,T. Tetrahedron2015, 71, 7614-7619.
  2. Stereocontrolled Synthesis of Phosphinyl Dipeptide Isosteres Using an Asymmetric Center at the Phosphorus Atom. Yamagishi, T. YAKUGAKU ZASSHI 2014, 134, 915-924.
  3. One-Pot Synthesis of Phenol Derivatives by the Novel Intramolecular Alder-Rickert Reaction: Effects of Aryl Substituent at the 3-Position of Cyclohexenone Derivatives on Reactivity. Kinbara, A.; Yamagishi, T.; Fujishige, T.; Miyaoka, H. Chem. Pharm. Bull. 2013, 61, 768-775.
  4. Total Synthesis and Structural Revision of Incargutines A and B. Kinbara, A.; Yamagishi, T.; Ouchi, H.; Miyaoka, H. Synlett 2013, 24, 1998-2002.
  5. Diastereoselective Synthesis of Pro-Phe Phosphinyl Dipeptide Isosteres. Yamagishi, T.; Kinbara, A.; Okubo, N.; Sato, S.; Fukaya, H. Tetrahedron: Asymmetry 2012, 23, 1633-1639.
  6. Synthesis of Phenol Derivatives from Cyclohex-2-enones Bearing an Alkyne through Lewis Acid-Catalyzed Enolization and Intramolecular Alder-Rickert Reaction. Kinbara, A.; Yamagishi, T.; Hanzawa, N.; Kawashima, E.; Miyaoka, H. J. Org. Chem. 2012, 77, 8999-9005.
  7. A Safe and Scalable Procedure for Preparation of α-Picoline-Borane from Sodium Mono-acyloxyborohydrides and α-Picoline. Kawase, Y.; Yamagishi, T.; Kutsuma, T.; Zhibao, H.; Yamamoto, Y.; Kimura, T.; Nakata, T.; Kataoka, T.; Yokomatsu, T. Org. Process Res. Dev. 2012, 16, 495-498.
  8. Diastereoselective Synthesis of the Leu-Pro Type Phosphinyl Dipeptide Isostere. Yamagishi, T.; Tashiro, N.; Yokomatsu, T. J. Org. Chem. 2011, 76, 5472-5476.
  9. A Chemo-enzymatic Synthesis of Optically Active 1,1-Diethoxyethyl(aminomethyl)phosphinates: Useful Chiral Building Blocks for Phosphinyl Dipeptide Isosteres. Yamagishi, T.; Mori, J.; Haruki, T.; Yokomatsu, T. Tetrahedron: Asymmetry 2011, 22, 1358-1363.
所属学会・団体名
  • 日本薬学会
  • 日本化学会
  • 有機合成化学協会

E-mail

t-yamagishi@pha.ohu-u.ac.jp